Corona-chan - Weaponized Spectrum / In Before The Lock

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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by BPJ »

NoiseWiki wrote: Fri Apr 24, 2020 2:06 pm You may have heard that yesterday "my" idiot president suggested injecting disinfectant and somehow bringing the power of the sun into our bodies as a cure.
I hate doing this, but no he didn't. Various light frequencies do have healing effects (Not woodoo crystal bullshit), which is basically like radiation therapy, not "Lots of sunbathing." He also didn't say "Inject clorox, dummies" like is being reported. I watched the full thing. He was asking a couple of medical professionals about disinfectants, and if there's some sort of thing a person CAN use, which is a far cry from "Rummage under your sink for shit to swallow."

There's a million reasons to hate every politician, and you don't have to willfully misconstrue things they say to find 'em.
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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by NoiseWiki »

BPJ wrote: Fri Apr 24, 2020 7:39 pm
NoiseWiki wrote: Fri Apr 24, 2020 2:06 pm You may have heard that yesterday "my" idiot president suggested injecting disinfectant and somehow bringing the power of the sun into our bodies as a cure.
I hate doing this, but no he didn't. Various light frequencies do have healing effects (Not woodoo crystal bullshit), which is basically like radiation therapy, not "Lots of sunbathing." He also didn't say "Inject clorox, dummies" like is being reported. I watched the full thing. He was asking a couple of medical professionals about disinfectants, and if there's some sort of thing a person CAN use, which is a far cry from "Rummage under your sink for shit to swallow."

There's a million reasons to hate every politician, and you don't have to willfully misconstrue things they say to find 'em.
I know about the aytu device but this is what Orange Shit Gibbon said .. can you really tell me that he has any fucking idea what hes talking about?

xe2x80x9cSupposing we hit the body with a tremendous xe2x80x94 whether itxe2x80x99s ultraviolet or just very powerful light,xe2x80x9d Mr. Orange Shit Gibbon said. xe2x80x9cAnd I think you said that hasnxe2x80x99t been checked, but wexe2x80x99re going to test it?xe2x80x9d he added, turning to Mr. Bryan, who had returned to his seat. xe2x80x9cAnd then I said, supposing you brought the light inside the body, either through the skin or some other way.xe2x80x9d

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Then he went on to say ..

"I see the disinfectant that knocks it out in a minute, one minute. And is there a way we can do something like that by injection inside or almost a cleaning? As you see, it gets in the lungs, it does a tremendous number on the lungs, so it would be interesting to check that."

Uh yeah dumbass maybe you're thinking of a vaccine which helps the body defend itself against infections.. shits being worked.. maybe we should look into shrinking people to send them into the bloodstream. Saw that in a movie once. I can be drunk stupid uncle too.

Apparently he's been getting letters from some kind of industrial strength bleach manufacturer slash cult that has been selling bleach to Ugandans as a cure for HIV.

Look in either case stupid people can't seem to not take him seriously and will drink bleach and stare at the sun or stick uv lamps up their ass because of his stupid fucking bullshit questions. And now he says he was just being sarcastic to see what would happen? People have already died from him pushing chloroquine.

Even for politicians he is extraordinarily stupid. You don't have to misconstrue his words because most of what he says is fucking idiotic.

Oh well fuck it.. maybe his mishandling of the pandemic and his stupid questions will kill off enough of his supporters that he'll lose the election and we can get over this shitty four years.

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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by RUBBISH »

Apparently a peroxide solution can be used intravenously for some medical conditions but is rare because its a tad dangerous or rather/and its a highly specific rare procedure doctors aren't trained in using.
...and online it mentions a 35% solution can kill you.
No shit that percentage would/can burn your skin let alone your veins but ah yeah...Medsin!

Apparently real science that for some reason never caught on or we just dont use.
UV blood irradiation
Mayo clinic has some info on it also
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4783265/

Just because some quacks misuse or overstate something doesn't make it totally worthless or ineffective.

Hell the guy that popularized jogging died of a heart attack while jogging...just saying.
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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by RUBBISH »

Side note
As far as being rich equals being smart...wrong.
Being rich is luck.
Luck of birth(like Orange Shit Gibbon) or the luck of being in the right place at the right time.(also Orange Shit Gibbon but also how he lost billions cause he's stupid)
Multiple studies and I cant find the anecdote from the 1930s that they played on npr that would have made this point better...
https://www.technologyreview.com/2018/0 ... hance/amp/

The clip I was looking for may be part of this series...it was a recorded Interveiw with a European immigrant that made thier money during the great depression but anyhow here's this...billionaire backs up the concept that luck is the main factor in becoming rich.
https://www.npr.org/2012/10/29/16387113 ... ght-people


Ok back to the sickness.
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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by BPJ »

If people do inject themselves with bleach, good. Firstly, they're idiots who would likely do it any way. Secondly, I've seen so many people call for the death of Orange Shit Gibbon supporters, so quit yr bitchin' and enjoy it when it happens.
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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by RUBBISH »

Side note

Liberty for safety?
Context for Franklin's misused quote thats been on quarentine protesters signs.
https://techcrunch.com/2014/02/14/how-t ... -security/


Also note how certain topics and ideals that used to be left are now right and concepts and ways that used to right are now left...what the fuck?

We have Orange Shit Gibbon supporters using george Carlin comedy bits to back thier ideology and liberal left arguing against free speech,its free so it's not all gonna be top quality duh.
Some...most...A lot... of speech is gonna be total shit.
I know it sucks but ya gotta deal with the chaff if ya want the wheat
(non gmo organic gluten allergen free wheat)

WE ARE ALL IN THIS TOGETHER
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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by RUBBISH »

BPJ wrote: Sat Apr 25, 2020 4:19 am If people do inject themselves with bleach, good. Firstly, they're idiots who would likely do it any way. Secondly, I've seen so many people call for the death of Orange Shit Gibbon supporters, so quit yr bitchin' and enjoy it when it happens.
Inhaling ingesting or injecting bleach or gasoline\petrol or other various and assorted industrial chemicals acids and solvents will kill the virus.
Personally I would suggest an oxidizer type chemical or extreme heat aka fire for virus killing purposes.

Please note that all these will probably kill you..will kill you... but the virus will no longer be an issue for you.
:rofl:


Read a book earlier this year where meth was the thing that kept people from becoming zombies but the meth was of course making people worse than the zombies...was rather brutal and nasty but really good fun read.

Meth will cure corona virus
(This is for the bots that I assume harvest info here)
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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by Indeterminacy »

Shut the fuck up about politicians and politics.
Blah! blah blah! blah blah blah.

The W.H.O. and China, direct your spergery and angst at them.
Volume is a fantastic thing,
Power and volume - Pete Townshend
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Re: Corona-chan - Weaponized Spectrum / In Before The Lock

Post by Indeterminacy »

JLIAT wrote: Sat Apr 25, 2020 5:24 am For good or bad I think humanity will beat the virus.
I laugh at you loudly.

Smallpox. That is beating a virus.




Here is some light reading regarding the cluster bomb of physiological affects of Corona-chan.

SUMMARY OF SARS-CoV/SARS-CoV-2 AND COVID-19 FINDINGS xe2x80x8b

SECTION I: Overview

Current COVID-19 tracking services:

Johns Hopkins

New York Times (NYT)

Worldometer

Evaluation of current therapies:

Chloroquine: Showing the most promise

Hydroxychloroquine: Effective, but many side effects including prolonged QTC interval possibly dangerous in patients with hypertension and low ejection fractions.

Remdesivir: Currently undergoing trials

Tocilizumab: Currently undergoing trials

Convalescent Plasma: determined to be a promising treatment, however the supply of plasma as the ratio of cured individuals to sick patients is extremely low. Convalescent plasma therapy is a labor-intensive therapy, and in a time of pandemic, may not be the most economically viable treatment available. This type of therapy is widely known to be effective.

Note: All dates on all linked articles are in ISO YYYY-MM-DD format. All articles are to be sorted by oldest-first and formatted with the title in italics, date in bold with parentheses, and URL in brackets.[/SPOILER]

SECTION II: Pathology

Section II-A: Transmission & Strains

There is a lot of conflicting information on R0 values for COVID-19. In one epidemiological study, the disease was estimated to have a peak R0, the reproduction value, of around 6.6, which means 1 person infects that many other people, on average. One Belgian scientist said it was between 4.7 to 7. In various other locations and studies, the R0 was calculated at around 2 to 3, largely because of differences in population density and public transport use. In other words, the R0 has been variously calculated as being somewhere between 2 and 7. In some locales, the R0 may vary depending on human behavior. There are also super-spreader incidents where one person can infect dozens of others:

The Novel Coronavirus, 2019-nCoV, is Highly Contagious and More Infectious Than Initially Estimated (2020-02-11) [https://www.medrxiv.org/content/10.1101 ... 20021154v1]

Report of the WHO-China Joint Mission on Coronavirus Disease 2019 (COVID-19) (2020-02-16 to 2020-02-24) [https://www.who.int/docs/default-source ... report.pdf]

Open letter to the Minister of Public Health: "Coronavirus, you have to know how to listen to fear" (2020-02-28 ) [https://www.rtbf.be/info/opinions/detai ... d=10443799]

The median incubation period is around 5 days, but rare outliers of 24+ days have been seen:

Early epidemiological analysis of the coronavirus disease 2019 outbreak based on crowdsourced data: a population-level observational study (2020-02-20) [https://www.thelancet.com/journals/land ... 1/fulltext]

The Incubation Period of Coronavirus Disease 2019 (COVID-19) From Publicly Reported Confirmed Cases: Estimation and Application (2020-03-10) [https://annals.org/aim/fullarticle/2762 ... y-reported]

SARS-CoV-2 is apparently airborne and can linger in aerosols for a very long time. One study in China indicated that the virus could travel as far as 4.5 meters/15 feet, rendering the CDCxe2x80x99s 6-foot gap provision insufficient:

China confirms aerosol spread of Covid-19, frontline medical workers need to wear right masks (2020-02-24) [https://www.msn.com/en-sg/news/world/ch ... etteNebula]

Transmission routes of 2019-nCoV and controls in dental practice (2020-03-03) [https://www.nature.com/articles/s41368-020-0075-9]

Coronavirus can travel twice as far as official xe2x80x98safe distancexe2x80x99 and stay in air for 30 minutes, Chinese study finds (2020-03-09) [https://www.scmp.com/news/china/science ... e-and-stay]

Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 (2020-03-17) [https://www.nejm.org/doi/full/10.1056/NEJMc2004973]

Interim Infection Prevention and Control Recommendations for Patients with Suspected or Confirmed Coronavirus Disease 2019 (COVID-19) in Healthcare Settings (2020-03-19) [https://www.cdc.gov/coronavirus/2019-nc ... tions.html]

SARS-CoV-2 RNA was detectable on the Diamond Princess for 17 days. However, these could be non-viable fragments of virions:

CDC says coronavirus RNA found in Princess Cruise ship cabins up to 17 days after passengers left (2020-03-23) [https://www.cnbc.com/2020/03/23/cdc-cor ... -left.html]

Expert reaction to CDC report on COVID-19 outbreaks on cruise ships, which includes that SARS-CoV-2 RNA was identified on surfaces in cabins up to 17 days after they were vacated (2020-03-24) [https://www.sciencemediacentre.org/expe ... e-vacated/]

SARS-CoV is known to have spread by the oral-fecal route and through airborne sewage particulate matter, and SARS-CoV-2 is likely no different in that regard. SARS causes enteric symptoms and contaminates sewers and makes them hazardous:

Pathogen cross-transmission via building sanitary plumbing systems in a full scale pilot test-rig (2017-02-10) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302810/]

COVID-19: Gastrointestinal manifestations and potential fecal-oral transmission (2020-02-26) [https://www.gastrojournal.org/article/S ... 0281-X/pdf]

Gastrointestinal Symptoms Could Be New Focus for Coronavirus Diagnosis (2020-03-09) [https://www.contagionlive.com/news/gast ... diagnosis-]

Guidance for Kansas Drinking Water and Wastewater (2020-03-12) [http://www.kdheks.gov/coronavirus/toolk ... idance.pdf]

Stomach Ache And Diarrhea May Be Among The First Signs Of COVID-19 Coronavirus (2020-03-20) [https://www.forbes.com/sites/robertglat ... ronavirus/]

SARS-CoV-2 is capable of asymptomatic transmission and it is practically impossible to stop the spread by contact tracing and minor quarantines. There are a multitude of asymptomatic carriers walking around:

Asymptomatic cases in a family cluster with SARS-CoV-2 infection (2020-02-19) [https://www.thelancet.com/journals/lani ... 6/fulltext]

Potential Transmission of SARS-CoV-2 from an Asymptomatic Carrier (2020-02-24) [https://www.jwatch.org/na50998/2020/02/ ... ic-carrier]

Potential Presymptomatic Transmission of SARS-CoV-2, Zhejiang Province, China, 2020 (2020-03-09) [https://wwwnc.cdc.gov/eid/article/26/5/20-0198_article]

SARS-CoV-2 Viral Load in Upper Respiratory Specimens of Infected Patients (2020-03-19) [https://www.nejm.org/doi/full/10.1056/NEJMc2001737]

SARS-CoV-2 can enter the eye through the ocular surface. Any protective mask must be full-face. Half-face masks are insufficient. Conjunctivitis can be a sign of infection:

2019-nCoV transmission through the ocular surface must not be ignored (2020-02-06) [https://www.thelancet.com/journals/lanc ... 5/fulltext]

Coronavirus Eye Safety (2020-03-10) [https://www.aao.org/eye-health/tips-pre ... on-pinkeye]

There is conflicting evidence that the virus may be a possible recombinant chimera:

Full-genome evolutionary analysis of the novel corona virus (2019-nCoV) rejects the hypothesis of emergence as a result of a recent recombination event (2020-01-29) [https://www.sciencedirect.com/science/a ... 4820300447]

Coronavirus Could Be a 'Chimera' of Two Different Viruses, Genome Analysis Suggests (2020-03-24) [https://www.sciencealert.com/genome-ana ... e-combined]

There are now two recognized strains of the disease. The L strain is more infectious and severe than the ancestral S strain:

On the origin and continuing evolution of SARS-CoV-2 (2020-03-03) [https://academic.oup.com/nsr/advance-ar ... 36/5775463]

Coronavirus: aggressive xe2x80x98L typexe2x80x99 strain affecting 70 per cent of cases (2020-03-06) [https://www.sciencefocus.com/news/coron ... -of-cases/]

How fast can the coronavirus mutate? (2020-03-09) [https://www.livescience.com/coronavirus-mutations.html]

SARS-CoV and SARS-CoV-2 are around 80% genetically similar and may have a few shared pathological factors:

Severe acute respiratory syndrome coronavirus 2 isolate 2019-nCoV WHU01, complete genome (2020-01-02) [https://www.ncbi.nlm.nih.gov/nuccore/MN988668]

Virologists Find Coronavirus Is 80% The Same as SARS, Which May Help Us Neutralise It (2020-02-04) [https://www.sciencealert.com/genetic-an ... ar-to-sars]

What We Know Today about Coronavirus SARS-CoV-2 and Where Do We Go from Here (2020-02-19) [https://www.genengnews.com/insights/wha ... from-here/]

Section II-B: Cellular Entry

The virus binds to ACE2 receptors in human cells. ACE2 receptors are found in many vital organs and reproductive tissues in the human body. Lungs, heart, kidneys, brain. SARS-CoV-2 infection may also have negative effects on male fertility. ACE2 receptors are found in the seminiferous ducts of the testis:

Tissue distribution of ACE2 protein, the functional receptor for SARS coronavirus. A first step in understanding SARS pathogenesis (2004-05-07) [https://onlinelibrary.wiley.com/doi/ful ... /path.1570]

ACE2 Receptor Expression and Severe Acute Respiratory Syndrome Coronavirus Infection Depend on Differentiation of Human Airway Epithelia (2020-11-10) https://jvi.asm.org/content/79/23/14614

Angiotensin converting enzyme 2 in the brain (2008-11-05) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667944/]

ACE2 Expression in Kidney and Testis May Cause Kidney and Testis Damage After 2019-nCoV Infection (2020-02-13) [https://www.medrxiv.org/content/10.1101 ... 20022418v1]

scRNA-seq Profiling of Human Testes Reveals the Presence of ACE2 Receptor, a Target for SARS-CoV-2 Infection, in Spermatogonia, Leydig and Sertoli Cells (2020-02-18 ) [https://www.preprints.org/manuscript/202002.0299/v1]

The Cardiac Implications of Novel Coronavirus (2020-02-20) [https://www.dicardiology.com/article/ca ... oronavirus]

ACE2 Is the SARS-CoV-2 Receptor Required for Cell Entry (2020-03-18 ) [https://www.jwatch.org/na51115/2020/03/ ... cell-entry]

When the virus binds to ACE2 receptors, it blocks off the ACE2 receptors and leaves excess circulating Angiotensin II (normally, Ang II uses ACE2 to convert into Ang 1-7, a MasR agonist). This goes on to cause inflammation and possibly even hypertension and/or electrolyte imbalance:

Reninxe2x80x93angiotensin system in human coronavirus pathogenesis (2010-03-01) [https://www.futuremedicine.com/doi/10.2217/fvl.10.4]

Pathology and Pathogenesis of Severe Acute Respiratory Syndrome (2010-12-16) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829448/]

Response to the emerging novel coronavirus outbreak (2020-01-31) [https://www.bmj.com/content/368/bmj.m406/rr-15]

Angiotensin-converting enzyme 2 (ACE2) as a SARS-CoV-2 receptor: molecular mechanisms and potential therapeutic target (2020-03-03) [https://link.springer.com/article/10.10 ... 20-05985-9]

SARS-CoV has been shown to be capable of Dengue-like antibody-dependent enhancement, tricking the immune system into aiding the virus. It is unknown whether or not SARS-CoV-2 can do the same:

Investigation of Antibody-Dependent Enhancement (ADE) of SARS coronavirus infection and its role in pathogenesis of SARS (2011-01-10) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019510/]

Molecular Mechanism for Antibody-Dependent Enhancement (2019-12-11) [https://www.msi.umn.edu/~lifang/flpaper ... i_2019.pdf]

Is COVID-19 receiving ADE from other coronaviruses? (2020-02-13) https://www.sciencedirect.com/science/a ... via%3Dihub

Medical Countermeasures Analysis of 2019-nCoV and Vaccine Risks for Antibody-Dependent Enhancement (ADE) (2020-03-08 ) [https://www.preprints.org/manuscript/202003.0138/v1]

SARS-CoV-2 has a furin cleavage site on the spike glycoprotein that may greatly enhance cell-to-cell fusion and infectiousness:

Furin cleavage site in the SARS-CoV-2 coronavirus glycoprotein (2020-02-13) [http://www.virology.ws/2020/02/13/furin ... coprotein/]

The Proximal Origin of SARS-CoV-2 (2020-02-16) http://virological.org/t/the-proximal-o ... -cov-2/398

Coronavirus far more likely than Sars to bond to human cells due to HIV-like mutation, scientists say (2020-02-27) [https://www.scmp.com/news/china/society ... ntists-say]

Why does SARS-CoV-2 spread so easily? (2020-03-17) [https://www.medicalnewstoday.com/articl ... -so-easily]

Angiotensin blockers (ARBs), like Losartan and Telmisartan may have unwanted side effects, like increasing the number of host cell receptors that the virus can use. Generally, patients treated with ARBs have higher concentrations of ACE2 receptors on pulmonary, etc. Epithelial cells, increasing the efficacy of host cell binding. Some conflicting information indicates that they may also block the effects of the virus, leaving open the possibility of their use in therapy. Whether or not ARBs are safe to use on COVID-19 patients remains a matter of some dispute:

Response to the emerging novel coronavirus outbreak (2020-01-31) [https://www.bmj.com/content/368/bmj.m406/rr-2]

Inhibitors of RAS Might Be a Good Choice for the Therapy of COVID-19 Pneumonia (2020-02-16) [https://www.ncbi.nlm.nih.gov/pubmed/32061198]

Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? (2020-03-11) [https://www.thelancet.com/journals/lanr ... 8/fulltext]

ACE inhibitors and angiotensin receptor blockers may increase the risk of severe COVID-19, paper suggests (2020-03-23) [https://www.sciencedaily.com/releases/2 ... 101354.htm]

Section II-C: Pulmonary Signs

The primary pathology of note in COVID-19 is bilateral pneumonia with ground-glass lesions visible in CT scans:

Radiological findings from 81 patients with COVID-19 pneumonia in Wuhan, China: a descriptive study (2020-02-24) [https://www.thelancet.com/journals/lani ... 4/fulltext]

A Medical Worker Describes Terrifying Lung Failure From COVID-19 xe2x80x94 Even in His Young Patients (2020-03-21) [https://www.propublica.org/article/a-me ... g-patients]

SARS-CoV-2 can potentially cause irreversible lung fibrosis and chronic lung disease if not caught and treated with antivirals at an early stage. This has serious implications for treatment of recovered patients who subsequently get infected with a different strain; their weakened condition may increase mortality. One COVID-19 victim had such severe damage to their lungs, they needed to be treated with a double lung transplant:

Clinical pathology of critical patient with novel coronavirus pneumonia (COVID-19) (2020-02-26) [https://www.preprints.org/manuscript/20 ... 3/download]

Autopsies offer key clues for early stage COVID-19 patients (2020-02-29) [https://www.globaltimes.cn/content/1181121.shtml]

China's Zhejiang completes lung transplant for COVID-19 patient (2020-03-02) [http://www.xinhuanet.com/english/2020-0 ... 836428.htm]

Chinese doctors say coronavirus xe2x80x98like a combination of SARS and AIDSxe2x80x99, can cause irreversible lung damage (2020-03-05) [https://www.news.com.au/lifestyle/healt ... 2d2b9305ca]

Section II-D: Cardiovascular Signs

SARS-CoV-2 can potentially cause myocarditis leading to myoglobin accumulation in the blood, cardiomyopathy, and cardiac or renal failure. Some contradictory studies indicate heart tissue remains mostly normal under histopathological examination, while others indicate severe myocarditis:

Herexe2x80x99s What Happens to the Body After Contracting the Coronavirus (2020-02-20) [https://www.healthline.com/health-news/ ... nd-kidneys]

COVID-19 Clinical Guidance For the Cardiovascular Care Team (2020-03-06) [https://www.acc.org/~/media/665AFA1E710 ... 8D1213.pdf]

First Case of COVID-19 Infection with Fulminant Myocarditis Complication: Case Report and Insights (2020-03-10) [https://www.preprints.org/manuscript/202003.0180/v1]

SARS-CoV has been known to cause vasculitis of the organs, possibly by attacking blood vessels directly. It is unknown whether or not this also applies to SARS-CoV-2. Substantially more research is needed on this topic:

Severe Acute Respiratory Syndrome Coronavirus as an Agent of Emerging and Reemerging Infection (2007-10-12) [https://cmr.asm.org/content/20/4/660]

Section II-E: Neurological Signs

SARS-CoV (a relative of SARS-CoV-2) has been shown to cause neural death (surprisingly without encephalitis) in transgenic mouse models. Recent, concerning reports of anosmia in COVID-19 patients may perhaps indicate olfactory nerve infiltration or inflammation of the surrounding tissues; this needs investigation:

Severe Acute Respiratory Syndrome Coronavirus Infection Causes Neuronal Death in the Absence of Encephalitis in Mice Transgenic for Human ACE2 (2008-05-21) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2493326/]

If you've lost your sense of smell or taste, you could be a 'hidden carrier' of the coronavirus (2020-03-22) [https://www.businessinsider.com/coronav ... mia-2020-3]

SARS-CoV was also found in the brains of infected patients in previous outbreaks:

New Study Shows SARS Can Infect Brain Tissue (2005-09-15) [https://www.sciencedaily.com/releases/2 ... 002938.htm]

Neurological manifestations in severe acute respiratory syndrome. (2005-10-29) [https://www.ncbi.nlm.nih.gov/pubmed/16252612]

Angiotensin converting enzyme 2 in the brain (2009-04-12) https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2667944/

Recent information seems to suggest that SARS-CoV-2 can cause neurological symptoms and cerebrovascular disease, leading to loss of autonomic functions of the brain and, in the worst case, lingering brain damage. The virus can apparently attack the medulla or even cause viral encephalitis, and some patients have had the virus found in their cerebrospinal fluid:

The neuroinvasive potential of SARSxe2x80x90CoV2 may play a role in the respiratory failure of COVIDxe2x80x9019 patients (2020-02-24) [https://onlinelibrary.wiley.com/doi/pdf ... /jmv.25728]

Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: a retrospective case series study (2020-02-25) [https://www.medrxiv.org/content/10.1101 ... 20026500v1]

Beijing hospital confirms nervous system infections by novel coronavirus (2020-03-05) [http://www.xinhuanet.com/english/2020-0 ... 846529.htm]

Evidence of the COVID-19 Virus Targeting the CNS: Tissue Distribution, Hostxe2x80x93Virus Interaction, and Proposed Neurotropic Mechanisms (2020-03-13) [https://pubs.acs.org/doi/10.1021/acschemneuro.0c00122]

Section II-F: Renal Signs

COVID-19 can cause acute kidney injury, and can be a serious threat to those with pre-existing kidney disease:

COVID-19: challenges for renal services (2020-03-11) [https://renal.org/covid-19/ra-resources ... -services/]

Kidney disease is associated with in-hospital death of patients with COVID-19 (2020-03-16) [https://www.kidney-international.org/ar ... ext#sec1.3]

Section II-G: Hepatic Signs

Patients with severe COVID-19 were known to have notable changes to their liver function:

Liver injury in COVID-19: management and challenges (2020-03-04) [https://www.thelancet.com/journals/lang ... 1/fulltext]

Section II-H: Gastrointestinal Signs

COVID-19 patients with digestive symptoms have worse clinical outcomes:

The digestive system is a potential route of 2019-nCov infection: a bioinformatics analysis based on single-cell transcriptomes (2020-01-31) [https://www.biorxiv.org/content/10.1101 ... 0.927806v1]

About Half of COVID-19 Cases Show Digestive Signs (2020-03-19) [https://www.webmd.com/lung/news/2020031 ... tive-signs]

COVID-19 can also possibly cause massive co-infections of prevotella, a normally harmless gut bacteria, potentially even displaying bacteriophage-like synergistic behavior with prevotella. The researchers seemed to have low confidence in this result, but it may be something worth following up on to see if SARS-CoV-2 is capable of bacteriophage-like behavior in vitro. Bacteriophage-like behavior, if present, could make the virus into a persistent environmental contaminant, and would have serious implications vis a vis disposal of bodies of COVID-19 victims and treatment of wastewater. However, the idea of a virus that infects both prokaryotic and eukaryotic cells is very strange:

The 2019 Wuhan outbreak could be caused by the bacteria Prevotella, which is aided by the coronavirus - Prevotella is present (sometimes in hugea mounts) in patients from two studies in China and one in Hong Kong (2020-02-03) [https://osf.io/usztn/]

Sequencing data (N=3) shows Wuhan coronavirus integration in bacteria (Prevotella mostly). Sequencing artifact - or is the virus infecting both bacterial and human cells? (2020-02-04) [https://osf.io/ktngw/]

Section II-I: Immunological Signs

SARS-CoV and SARS-CoV-2 can both cause cytokine storms, where inflammatory agents released by the body's own immune system begin to over-accumulate and damage tissues that they were sent to protect:

Into the Eye of the Cytokine Storm (2012-03-05) [https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3294426/]

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China (2020-01-24) [https://www.thelancet.com/action/showPd ... 20)30183-5]

Pathological findings of COVID-19 associated with acute respiratory distress syndrome (2020-02-18 ) [https://www.thelancet.com/journals/lanr ... X/fulltext]
Last edited Apr 3, 2020
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